Looking up, I observe the immensity of the cosmos; bowing my head, I examine the multitude of the world. Thus, I let my eyes wander and my mind roam freely, fully enjoying the pleasures of sight and sound—what a true delight it is!
仰观宇宙之大,俯察品类之盛,所以游目骋怀,足以极视听之娱,信可乐也。
Academic Profile
Medical Doctor (M.D.), specializing in:
Evolutionary genomics and comparative genomics to analyze adaptive evolution and neural regenerative capacity;
Bioinformatics and patch-clamp neuroelectrophysiology to investigate spinal cord development patterns, molecular mechanisms, intrinsic regenerative pathways, and microenvironment reconstruction for spinal repair and functional recovery;
Molecular mechanisms and therapeutic agents for neurodegenerative diseases in Parkinson’s models.
Professional Experience
Former Roles:
First Research Assistant to Academician, Key Laboratory of Neuroregeneration, Ministry of Education, Jiangsu Province;
Director of Bioinformatics and Patch-Clamp Electrophysiology Platform, Key Laboratory of Neuroregeneration (MOE);
Experimentalist, NMPA Key Laboratory for Tissue Engineering Technology Products Research and Evaluation.
Current:
Neurologist, Neurological Disease Center, Deyang People’s Hospital Affiliated to Chengdu University of Traditional Chinese Medicine.
Research Focus
Long-term dedication to multi-omics integration (genomics, transcriptomics) combined with experimental validation to study:
Neurodegenerative diseases (e.g., Parkinson’s pathology);
Neural development and regenerative repair mechanisms;
Spinal cord regeneration microenvironment reconstruction via bioinformatics and patch-clamp electrophysiology.
Key Achievements
Publications:
23 SCI-indexed papers with cumulative Impact Factor: 174.2
5 papers with IF > 10 (5-year impact factor);
6 CAS Zone 1 papers (5 TOP journals);
10 CAS Zone 2 papers (4 TOP journals);
19 JCR Q1 papers, 3 JCR Q2 papers.
Research cited by Nature, Reuters, and Science and Technology Daily;
Oxford University Press "Top 10% Read" award.
Mentorship:
Supervised 3 Ph.D. candidates (Nanjing University of Chinese Medicine & Jiangsu Provincial Hospital of Traditional Chinese Medicine);
Guided 2 M.S. students (Neurobiology, Nantong University).
Projects & Grants:
Co-investigator:
3 NSFC General Projects;
1 NSFC Key Project (led by Academician);
1 Jiangsu Provincial Priority Academic Program;
1 Sichuan Provincial Key R&D Project.
Principal Investigator:
1 Talent Project (Nantong University);
1 MOE Key Laboratory Project (Tongji University).
Awards:
First Prize, Huaxia Medical Science and Technology Award;
Second Prize, Natural Science Award of MOE Higher Education Outstanding Research.
Leadership & Service
Director, Bioinformatics and Patch-Clamp Electrophysiology Platform, MOE Key Laboratory of Neuroregeneration;
Experimentalist, NMPA Key Laboratory for Tissue Engineering;
Founding Member:
China Spinal Cord Injury Repair and Functional Reconstruction Alliance;
CPAM Smart Healthcare and Intelligent Medicine Branch;
Senior Member, Jiangsu Association for Science and Technology;
Member, China Computer Federation (CCF);
Mentor for Ph.D./M.S. candidates (NJUCM & Jiangsu Provincial Hospital);
Lecturer, Bioinformatics Graduate Course, MOE Key Laboratory of Neuroregeneration (Nantong University);
Review Expert:
Research Equipment Bidding (Nantong University);
Entrance Exam Designer for Tertiary Hospitals;
First Research Assistant to Chinese Academy of Engineering Academician;
Peer Reviewer for multiple SCI journals (awarded "Outstanding Reviewer").
Work
People's Hospital of Deyang City
|
M.D.
China
Key Laboratory of Neuroregeneration of Jiangsu and the Ministry of Education
China
→
Education
Soochow University
China
→
Doctor of Medicine(M.D.)
Nantong University
China
→
Master's degree
Publications
Convergent and divergent transcriptional reprogramming of motor and sensory neurons underlying response to peripheral nerve injury
Journal of Advanced Research
journal-article
Genome-wide profiling and functional characterization of circular RNAs in neural development and injury: insights from a rat model research
Cellular and Molecular Life Sciences
journal-article
VCF2Dis: an ultra-fast and efficient tool to calculate pairwise genetic distance and construct population phylogeny from VCF files
GigaScience
journal-article
Bilateral Thalamic Edema Caused by Tentorial Galenic Dural Arteriovenous Fistula and Sinus Thrombosis: Successful Endovascular Therapy
Turkish Neurosurgery
journal-article
Biomimetic-inspired piezoelectric ovalbumin/BaTiO3 scaffolds synergizing with anisotropic topology for modulating Schwann cell and DRG behavior
International Journal of Biological Macromolecules
journal-article
VCF2PCACluster: a simple, fast and memory-efficient tool for principal component analysis of tens of millions of SNPs
BMC Bioinformatics
journal-article
Cartilage stem/progenitor cells‐derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model
Exosomes derived from primary cartilage stem/progenitor cells promote the repair of osteoarthritic chondrocytes by modulating immune responses
International Immunopharmacology
journal-article
Integrative mRNA and miRNA Expression Profiles from Developing Zebrafish Head Highlight Brain-Preference Genes and Regulatory Networks
Molecular Neurobiology
journal-article
NGenomeSyn: an easy-to-use and flexible tool for publication-ready visualization of syntenic relationships across multiple genomes
Bioinformatics
journal-article
Integrated analyses reveal evolutionarily conserved and specific injury response genes in dorsal root ganglion ( Article Type: Analysis)
Scientific Data
journal-article
Deciphering the dynamic niches and regeneration-associated transcriptional program of motoneurons following peripheral nerve injury
iScience
journal-article
Deciphering the dynamic niches and regeneration-associated transcriptional program of motoneurons following peripheral nerve injury
iScience
journal-article
Evolution of the ErbB gene family and analysis of regulators of Egfr expression during development of the rat spinal cord
Neural Regeneration Research
journal-article
Developmental Temporal Patterns and Molecular Network Features in the Transcriptome of Rat Spinal Cord (Section: Tissue engineering)
Engineering
journal-article
Klf2-Vav1-Rac1 axis promotes axon regeneration after peripheral nerve injury.
Experimental neurology
journal-article
Molecular Regulatory Mechanism and Toxicology of Neurodegenerative Processes in MPTP/Probenecid-Induced Progressive Parkinson’s Disease Mice Model Revealed by Transcriptome
Molecular Neurobiology
journal-article
Speciation and adaptive evolution reshape antioxidant enzymatic system diversity across the phylum Nematoda
BMC Biology
journal-article
Anisotropic ridge/groove microstructure for regulating morphology and biological function of Schwann cells
Applied Materials Today
journal-article
Comparison of neural stem/progenitor cells from adult Gecko japonicus and mouse spinal cords
Experimental Cell Research
journal-article
The Landscape of Gene Expression and Molecular Regulation Following Spinal Cord Hemisection in Rats
Frontiers in Molecular Neuroscience
journal-article
Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration.
Nature communications
journal-article
Different Astrocytic Activation between Adult Gekko japonicus and Rats during Wound Healing In Vitro.